CoQ10 supplementation is also associated with improved outcomes after heart failure:
AANP – COQ10 Helps Heart Failure Patients Survive – (Wednesday, May 29, 2013)–Researchers have reported on a breakthrough study that found that taking coenzyme Q10, or CoQ10, supplements improves overall survival in patients with moderate to severe heart failure. The two subject groups took either 100 milligrams of CoQ10 three times daily or placebo. Results at two years showed that the primary endpoint of major adverse cardiovascular event was reached by 14 percent in the CoQ10 group versus 25 percent of patients in the placebo group. Furthermore, at two years, in comparison to placebo, CoQ10-treated patients had a significantly lower cardiovascular mortality, fewer hospitalizations, and greater improvements in functionality. (This represents the first study with adequate evidence showing that CoQ10 improves survival in heart failure patients. Also, CoQ10 synthesis is inhibited by statins, drugs commonly prescribed to heart failure patients, which reduce serum levels of CoQ10 by up to 40 percent. These results are guideline changing, making a strong case for CoQ10 to be considered as part of the maintenance therapy for all patients with chronic heart failure.)