Vitamin D Slows Cancer Conversion

The latest from the AANP:

AANP – Vitamin D Slows Cell Change From Premalignant To Malignant State¬†–¬†(Monday,¬†November 26, 2012) –Scientists have concluded that vitamin D may act, by several mechanisms, to inhibit production and activity of a protein that promotes cell division and is linked to more than half of all cancers. The active form of vitamin D appears to inhibit the protein cMYC, which plays a role in the progression of a premalignant cell to a malignant one. (Poor dietary intake and sun avoidance has created vitamin D insufficiency in many populations worldwide, which may be a risk for a number of cancers, particularly cancers of the digestive tract, including colon cancer, and certain forms of leukemia.) The team found that vitamin D strongly stimulates the production of a natural antagonist of cMYC called MXD1, essentially shutting down cMYC function and keeping cell proliferation in check. The researchers encouraged people to maintain adequate vitamin D supplementation and encouraged other scientists to develop large, well-controlled cancer chemoprevention trials to test the effects of adequate supplementation. The findings were published in the November 2012 edition of Proceedings of the National Academy of Sciences. The full text is available at without cost.

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